ARFRP1 — ADP ribosylation factor related protein 1
ARFRP1 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ARFRP1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | T cell Survival T cell maturation | BCL2L1, C6orf47, CHD9, DAXX, DEF6, DENND2D, DHPS, ERGIC2 +26 more | |
| Mucosal-associated invariant T cell | Mitochondrial Biogenesis Mitochondrial & OxPhos | ARL2, ATP6V0E1, CALHM2, CCS, COA4, DBP, DENND2D, DMAC1 +15 more |
About the gene
| Synonyms | ARL18, ARP, Arp1 |
|---|---|
| Chromosome | 20: 63698642-63708025 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Predicted intracellular proteins |
Function
Trans-Golgi-associated GTPase that regulates protein sorting. Controls the targeting of ARL1 and its effector to the trans-Golgi. Required for the lipidation of chylomicrons in the intestine and required for VLDL lipidation in the liver
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.