DMAC1 — Distal membrane arm assembly component 1
DMAC1 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
DMAC1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Innate lymphoid cells | Oxidative Phosphorylation Mitochondrial & OxPhos | APEX1, ATP5F1A, CCNC, COA3, ESD, HDAC2, HINT2, LAMTOR1 +15 more | View in SCUBA |
| Lymphatic endothelial | Metabolic Housekeeping Housekeeping | CAPNS1, CYB5R3, DUT, EID1, ESD, GNAI2, ISCU, OCIAD1 +5 more | View in SCUBA |
| Macrophages | Complex I / NADH Dehydrogenase Mitochondrial & OxPhos | AHCY, ANP32A, ANTKMT, APEX1, ARL2, ATIC, ATP5F1A, ATP5ME +31 more | View in SCUBA |
| Mucosal-associated invariant T cell | Mitochondrial Biogenesis Mitochondrial & OxPhos | ARFRP1, ARL2, ATP6V0E1, CALHM2, CCS, COA4, DBP, DENND2D +15 more |
About the gene
| Synonyms | C9orf123, MGC4730, TMEM261 |
|---|---|
| Chromosome | 9: 7796500-7888380 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Predicted membrane proteins |
Function
Required for the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Involved in the assembly of the distal region of complex I
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.