BORCS5 — BLOC-1 related complex subunit 5
BORCS5 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
BORCS5's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | IFN-gamma Receptor Signaling Inflammation | CCDC93, CDC42SE2, DHCR7, EML4, IFNGR1, PDE4B, PGRMC2, PLEKHA2 +3 more | |
| Mucosal-associated invariant T cell | TCR Signal Attenuation Immune regulation | AFF4, CENPC, CHD2, CRACR2A, CRYBG1, DUSP16, FAS, FNBP1 +8 more |
About the gene
| Synonyms | LOH12CR1, LOH1CR12 |
|---|---|
| Chromosome | 12: 12357078-12471233 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor. Thereby, it may indirectly play a role in cell spreading and motility
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.