CRYBG1 — Crystallin beta-gamma domain containing 1
CRYBG1 belongs to a gene co-expression module in 6 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CRYBG1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | TCR signaling TCR/AP1/NFKb pathway | AP3M2, ATP1B3, CREM, DCTN6, EZR, FAM177A1, FTH1, GCSAM +19 more | View in SCUBA |
| Gamma-delta T cells | TCR Inhibitory Signaling Exhaustion | AFF4, CBLB, CCNH, CCNT1, CHD2, FYN, ISG20, PARP8 +9 more | |
| Goblet cells | Colonocyte Metabolic Defense Mitochondrial & OxPhos | ACAA2, CAT, GLIPR2, MLXIP, PKDCC, SAMD5, SEMA6A, ZFHX3 | View in SCUBA |
| Innate lymphoid cells | Inflammasome Activation Inflammation | ANKRD28, AP3D1, ARHGEF7, CCNH, CD55, CDC42SE1, CHD7, CHKA +19 more | View in SCUBA |
| Mucosal-associated invariant T cell | TCR Signal Attenuation Immune regulation | AFF4, BORCS5, CENPC, CHD2, CRACR2A, DUSP16, FAS, FNBP1 +8 more | |
| Natural Killer cells | NK Cytotoxic Signaling Cytotoxicity | BCL2L11, CBLB, DAZAP2, FYN, GPATCH8, HNRNPUL1, MAPK1, RAPGEF1 +3 more | View in SCUBA |
About the gene
| Synonyms | AIM1, ST4 |
|---|---|
| Chromosome | 6: 106360717-106572017 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
May function as suppressor of malignant melanoma. It may exert its effects through interactions with the cytoskeleton
Human Protein Atlas · Open Targets
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.