CRIM1 — Cysteine rich transmembrane BMP regulator 1
CRIM1 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CRIM1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Cholesterol Biosynthesis Housekeeping | CSF1, HS3ST3B1, LDLR, MSMO1, MUC12, NDFIP2, REG1A, SQLE +1 more | |
| Lymphatic endothelial | Innate Immune Activation Immune regulation | CD46, CLTC, EIF2AK2, ENSA, FEZ2, GSN, PDLIM3, PON2 +9 more | View in SCUBA |
About the gene
| Synonyms | S52 |
|---|---|
| Chromosome | 2: 36355778-36551135 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins, Transporters |
Function
May play a role in CNS development by interacting with growth factors implicated in motor neuron differentiation and survival. May play a role in capillary formation and maintenance during angiogenesis. Modulates BMP activity by affecting its processing and delivery to the cell surface.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.