DEPP1 — DEPP1 autophagy regulator
DEPP1 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
DEPP1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | YAP Mechanotransduction migration & adhesion | COBLL1, CREB5, DST, FGL2, FLNC, FN1, GCNT2, GLIPR2 +7 more | View in SCUBA |
| Smooth muscle cells | NO-cGMP Signaling Contractility | AC005884.1, AC068888.1, AL355974.2, GUCY1A1, GUCY1B1, HIST1H4C, HOTAIRM1, REX1BD +2 more | View in SCUBA |
About the gene
| Synonyms | C10orf10, DEPP, FIG, Fseg |
|---|---|
| Chromosome | 10: 44970981-44978809 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Biological process | Autophagy |
Function
Acts as a critical modulator of FOXO3-induced autophagy via increased cellular ROS.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.