CREB5 — CAMP responsive element binding protein 5
CREB5 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CREB5's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | YAP Mechanotransduction migration & adhesion | COBLL1, DEPP1, DST, FGL2, FLNC, FN1, GCNT2, GLIPR2 +7 more | View in SCUBA |
| Glial cells | S100 Glial Activation Activation | CDC42EP5, CRIP2, EMP3, S100A10, S100A4, S100A6, TPPP3 | View in SCUBA |
| Monocytes | p38 MAPK Signaling Inflammatory | CRISPLD2, FBXL5, LBR, LRRK2, MAPK14, MEGF9, NFE2, NLRP12 +5 more | View in SCUBA |
| Neutrophils | PI3K Migration Signaling Migration & adhesion | CPPED1, CYTIP, PELI1, PTEN, RASSF3, SEMA4D, SH2D3C, SIRPB2 +3 more |
About the gene
| Synonyms | CRE-BPA, H_GS165L15.1 |
|---|---|
| Chromosome | 7: 28299321-28825894 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Transcription factors |
| Molecular function | Activator, DNA-binding |
| Biological process | Transcription, Transcription regulation |
Function
Binds to the cAMP response element and activates transcription
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.