GCNT2 — Glucosaminyl (N-acetyl) transferase 2 (I blood group)
GCNT2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GCNT2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | YAP Mechanotransduction migration & adhesion | COBLL1, CREB5, DEPP1, DST, FGL2, FLNC, FN1, GLIPR2 +7 more | View in SCUBA |
About the gene
| Synonyms | bA360O19.2, bA421M1.1, CCAT, GCNT5, IGNT, II, NACGT1, NAGCT1, ULG3 |
|---|---|
| Chromosome | 6: 10492223-10629368 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins |
| Molecular function | Glycosyltransferase, Transferase |
Function
Branching enzyme that converts linear into branched poly-N- acetyllactosaminoglycans. Introduces the blood group I antigen during embryonic development. It is closely associated with the development and maturation of erythroid cells. Determines the expression of the blood group I antigen in erythrocytes
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.