DIXDC1 — DIX domain containing 1
DIXDC1 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
DIXDC1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Macrophage Contamination Cell contamination | CCDC68, CLEC7A, CORO2A, CPVL, DOCK11, LPCAT4, PTGS1, ST8SIA4 +3 more | View in SCUBA |
| Fibroblasts | Notch Fibroblast Activation Developmental | CORO1C, DSTN, FHL1, MRGPRF, PDLIM5, RBPJ, SH3BGRL, TCEAL3 +2 more | View in SCUBA |
About the gene
| Synonyms | Dixin, KIAA1735 |
|---|---|
| Chromosome | 11: 111927144-112022653 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Actin-binding, Developmental protein |
| Biological process | Wnt signaling pathway |
Function
Positive effector of the Wnt signaling pathway; activates WNT3A signaling via DVL2. Regulates JNK activation by AXIN1 and DVL2
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.