MRGPRF — MAS related GPR family member F
MRGPRF belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
MRGPRF's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Notch Fibroblast Activation Developmental | CORO1C, DIXDC1, DSTN, FHL1, PDLIM5, RBPJ, SH3BGRL, TCEAL3 +2 more | View in SCUBA |
| Smooth muscle cells | Lysosomal Glycoprotein Catabolism Protein processing & ER | AKR7A2, CERCAM, CPQ, FCGRT, GRN, HEXB, LTBP1, PPIC | View in SCUBA |
About the gene
| Synonyms | GPR140, GPR168, MGC21621, mrgF |
|---|---|
| Chromosome | 11: 69004395-69013382 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters |
| Molecular function | G-protein coupled receptor, Receptor, Transducer |
Function
Orphan receptor. May bind to a neuropeptide and may regulate nociceptor function and/or development, including the sensation or modulation of pain (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.