ENPEP — Glutamyl aminopeptidase
ENPEP belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ENPEP's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Chylomicron lipid absorption Lipid metabolism | ACO2, ALDOB, ANPEP, CNDP2, DGAT1, FABP2, MOGAT2, MTTP +3 more | View in SCUBA |
| Smooth muscle cells | Capillary Pericyte Development | ADAP2, ADRA2A, ANKRD29, CCL8, CNGA1, EPHA2, EPS8L1, FAM162B +10 more | View in SCUBA |
About the gene
| Synonyms | CD249, gp160 |
|---|---|
| Chromosome | 4: 110365733-110565285 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | CD markers, Enzymes, Plasma proteins, Predicted membrane proteins |
| Molecular function | Aminopeptidase, Hydrolase, Metalloprotease, Protease |
Function
Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.