GBE1 — 1,4-alpha-glucan branching enzyme 1
GBE1 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GBE1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Inflammatory Lipid Metabolism Metabolite transfer | ACSL4, APOL1, CDK2AP2, COPS8, GOLM1, MAPRE1, NPC1, PDLIM7 +5 more | View in SCUBA |
| Macrophages | Macrophage Migration Migration & adhesion | CEMIP2, CPM, EPB41L2, EPS8, ITGA9, KCNQ1, MAN1A1, MEF2C +12 more | View in SCUBA |
About the gene
| Chromosome | 3: 81489703-81761645 |
|---|---|
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins |
| Molecular function | Glycosyltransferase, Transferase |
| Biological process | Glycogen biosynthesis |
Function
Glycogen-branching enzyme participates in the glycogen biosynthetic process along with glycogenin and glycogen synthase. Generates alpha-1,6-glucosidic branches from alpha-1,4-linked glucose chains, to increase solubility of the glycogen polymer.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.