GNGT2 — G protein subunit gamma transducin 2
GNGT2 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GNGT2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | AKT survival signaling TCR/AP1/NFKb pathway | ABHD2, AKT1, ARL14EP, ATF7, ATP6AP1, CHD8, IP6K2, ITSN2 +10 more | View in SCUBA |
| Monocytes | Non-classical Monocyte Lysosomal & pahgocytosis | ABI3, CAMK1, CD300A, CHCHD10, DAPK1, FCGR3A, ICAM2, ITM2B +5 more | View in SCUBA |
About the gene
| Synonyms | GNG9 |
|---|---|
| Chromosome | 17: 49202791-49210574 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, RAS pathway related proteins, Transporters |
| Molecular function | Transducer |
Function
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.