SCUBA

HOXA5 — Homeobox A5

HOXA5 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

HOXA5's module in each cell type

Cell typeModuleShares the module with
Innate lymphoid cellsNK ILC Tissue Homing
Homing & TEM
ADGRE5, AKAP13, AREG, ARL4C, ATP1B3, B3GNT7, BTG1, CCDC107 +25 moreView in SCUBA

About the gene

SynonymsHOX1, HOX1C
Chromosome7: 27141052-27143681
Predicted locationIntracellular
Essential geneNo
Protein classCancer-related genes, Predicted intracellular proteins, Transcription factors
Molecular functionDevelopmental protein, DNA-binding
Biological processTranscription, Transcription regulation

Function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Also binds to its own promoter. Binds specifically to the motif 5'-CYYNATTA[TG]Y-3'

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.