INSC — INSC spindle orientation adaptor protein
INSC belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
INSC's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | WNT-modulating Fibroblast Developmental | CIB2, COL4A5, DMKN, F3, FIP1L1, FRZB, GPSM3, HSD17B2 +9 more | View in SCUBA |
About the gene
| Chromosome | 11: 15112424-15247208 |
|---|---|
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Developmental protein |
| Biological process | Differentiation, Neurogenesis |
Function
May function as an adapter linking the Par3 complex to the GPSM1/GPSM2 complex. Involved in spindle orientation during mitosis. May regulate cell proliferation and differentiation in the developing nervous system. May play a role in the asymmetric division of fibroblasts and participate in the process of stratification of the squamous epithelium (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.