SCUBA

GPSM3 — G protein signaling modulator 3

GPSM3 belongs to a gene co-expression module in 8 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

GPSM3's module in each cell type

Cell typeModuleShares the module with
CD19⁺ B cellsB cell activation signaling
B cell maturation
ANKRD44, BLK, BTN3A2, EVI2B, GAPT, LBH, LTB, LY86 +9 moreView in SCUBA
CD4⁺ T cellsER stress UPR
Protein processing & ER
CCT2, CDK2AP2, CRELD2, DDX39A, DNAJB11, DSTN, EIF5A, GTF3A +9 moreView in SCUBA
FibroblastsWNT-modulating Fibroblast
Developmental
CIB2, COL4A5, DMKN, F3, FIP1L1, FRZB, HSD17B2, INSC +9 moreView in SCUBA
Gamma-delta T cellsTCR Proximal Signaling
TCR Signaling
ADGRG5, BIN2, C11orf21, C12orf75, CD300A, FGR, LAT, MATK +11 more
Innate lymphoid cellsILC1 Actin Motility
Cytoskeleton & motility
ACAP1, ARHGDIB, CORO1A, DGCR6L, EVL, HEXA, LCK, MFGE8 +14 moreView in SCUBA
MacrophagesTranslation Initiation
Housekeeping
AKR1B1, CAMLG, CAPZB, EEF1D, EEF2, EID1, EIF3D, EIF3E +26 moreView in SCUBA
Mucosal-associated invariant T cellMitochondrial Housekeeping
Mitochondrial & OxPhos
ARPC3, DUT, GNB2, LSM2, NAA38, NDUFB10, PLEKHJ1, REX1BD +7 more
NeutrophilsNeutrophil Motility Cytoskeleton
Migration & adhesion
CDKN2D, CNN2, COTL1, CST7, GLIPR1, GMFG, GNB2, JPT1 +9 more

About the gene

SynonymsAGS4, C6orf9, G18, G18.1a, G18.1b, G18.2, NG1
Chromosome6: 32190766-32195523
Predicted locationIntracellular
Essential geneNo
Protein classPredicted intracellular proteins

Function

Interacts with subunit of G(i) alpha proteins and regulates the activation of G(i) alpha proteins.

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.