LSAMP — Limbic system associated membrane protein
LSAMP belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
LSAMP's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Complement-producing Fibroblast Inflammatory | ANK2, C3, CLSTN3, CYP7B1, DAAM1, DHRS3, GUCY1A1, GUCY1B1 +8 more | View in SCUBA |
| Hematopoietic progenitor cells | Lymphoid Progenitor Commitment Lymphcyte development | BASP1, CCR9, LRRC38, LZTFL1, MME, OSBPL3, SCN3A, SH3BP5 +3 more |
About the gene
| Synonyms | IGLON3, LAMP |
|---|---|
| Chromosome | 3: 115802363-117139389 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins |
| Biological process | Cell adhesion |
Function
Mediates selective neuronal growth and axon targeting. Contributes to the guidance of developing axons and remodeling of mature circuits in the limbic system. Essential for normal growth of the hippocampal mossy fiber projection (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.