CCR9 — C-C motif chemokine receptor 9
CCR9 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CCR9's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Gut-homing Residence Tissue residence | ADAM28, ASB2, ATP8B4, CAPG, CD101, CD9, DAPK2, DENND1B +8 more | |
| Hematopoietic progenitor cells | Lymphoid Progenitor Commitment Lymphcyte development | BASP1, LRRC38, LSAMP, LZTFL1, MME, OSBPL3, SCN3A, SH3BP5 +3 more | |
| Mucosal-associated invariant T cell | Tc17 / MAIT17 Tc17 program | AHR, BAIAP2, CA10, GFPT2, HIC1, IL17A, IL2, ITGA1 +5 more | |
| Natural Killer cells | Gut-Homing NK Gut residency | FAM3C, GRAMD2B, OXNAD1, PLPP1, PRKAR2B, SMIM3, SNX9, TRAT1 | View in SCUBA |
About the gene
| Synonyms | CDw199, GPR-9-6, GPR28 |
|---|---|
| Chromosome | 3: 45884425-45903174 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins |
| Molecular function | G-protein coupled receptor, Receptor, Transducer |
| Biological process | Host-virus interaction |
Function
Receptor for chemokine SCYA25/TECK. Subsequently transduces a signal by increasing the intracellular calcium ions level. (Microbial infection) Alternative coreceptor with CD4 for HIV-1 infection
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.