CPQ — Carboxypeptidase Q
CPQ belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CPQ's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Lysosomal Biogenesis Vesicular traficking | APP, ATRAID, CST3, GLG1, GRN, HEXA, LGALS3BP, NDN +5 more | View in SCUBA |
| Glial cells | Glial Identity Homeostasis Housekeeping | ARPC1B, CMTM5, DDAH2, FCGRT, METRN, PON2, S100B, SLC22A17 +2 more | View in SCUBA |
| Neutrophils | Endocytic Vesicle Trafficking Vesicular traficking | NUMB, PACSIN2, PLXDC2, PREX1, RBM47, SBF2, TBL1X, TECPR2 +1 more | |
| Smooth muscle cells | Lysosomal Glycoprotein Catabolism Protein processing & ER | AKR7A2, CERCAM, FCGRT, GRN, HEXB, LTBP1, MRGPRF, PPIC | View in SCUBA |
About the gene
| Synonyms | LDP, PGCP |
|---|---|
| Chromosome | 8: 96645242-97149654 |
| Predicted location | Intracellular, Secreted |
| Essential gene | No |
| Protein class | Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins |
| Molecular function | Carboxypeptidase, Hydrolase, Metalloprotease, Protease |
Function
Carboxypeptidase that may play an important role in the hydrolysis of circulating peptides. Catalyzes the hydrolysis of dipeptides with unsubstituted terminals into amino acids. May play a role in the liberation of thyroxine hormone from its thyroglobulin (Tg) precursor
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.