PPIC — Peptidylprolyl isomerase C
PPIC belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PPIC's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | ECM Homeostasis ECM remodeling | CAST, CAVIN3, FAM114A1, HCFC1R1, MXRA7, SELENOW, TIMP2, TUBB | View in SCUBA |
| Goblet cells | ER Chaperone Glycosylation Protein processing & ER | ANG, ATP6V1G1, CD63, FKBP2, NANS, OST4, RABAC1, REEP5 +4 more | View in SCUBA |
| Pericytes | Type I Interferon Inflammatory | IFI16, IFI44L, IFI6, MX1, RCN1, SP100, TNFRSF1A, XAF1 | View in SCUBA |
| Smooth muscle cells | Lysosomal Glycoprotein Catabolism Protein processing & ER | AKR7A2, CERCAM, CPQ, FCGRT, GRN, HEXB, LTBP1, MRGPRF | View in SCUBA |
About the gene
| Synonyms | CYPC |
|---|---|
| Chromosome | 5: 123023250-123036725 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Predicted intracellular proteins |
| Molecular function | Isomerase, Rotamase |
Function
PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.