AFAP1L2 — Actin filament associated protein 1 like 2
AFAP1L2 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
AFAP1L2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD8⁺ T cells | Tissue residence Gut residence | FAM3C, HTRA1, KIR2DL4, KRT81, KRT86, NBL1, PLPP1, PTPN6 +1 more | View in SCUBA |
| Endothelial | Arterial EC Identity Endothelial cell development | BMP4, CFAP36, FUT8, ITPR2, JAG1, LTBP4, NEBL, NPTXR +6 more | View in SCUBA |
| Smooth muscle cells | Notch-TGFbeta Signaling Development | ACKR3, CSRNP3, GJC1, HTR1F, JAG1, LRRC10B, RAP2A, SLC38A11 +3 more | View in SCUBA |
About the gene
| Synonyms | Em:AC005383.4, FLJ14564, KIAA1914, XB130 |
|---|---|
| Chromosome | 10: 114294824-114404756 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.