PALM2AKAP2 — PALM2 and AKAP2 fusion
PALM2AKAP2 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PALM2AKAP2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Autophagy & Trafficking Housekeeping | ABCD2, ASCC3, ATG7, ATP9B, BTBD9, IKBKE, ITFG1, KLF12 +11 more | |
| Lymphatic endothelial | NF-κB Innate Signaling Inflammation | AKAP13, B4GALT5, BACH1, CHD2, CNST, DENND5A, HIVEP1, HIVEP2 +11 more | View in SCUBA |
About the gene
| Synonyms | PALM2-AKAP2 |
|---|---|
| Chromosome | 9: 109498325-110172512 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Binds to regulatory subunit (RII) of protein kinase A. May be involved in establishing polarity in signaling systems or in integrating PKA-RII isoforms with downstream effectors to capture, amplify and focus diffuse, trans-cellular signals carried by cAMP. Binds to and modulates the structure of the actin cytoskeleton
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.