PGM3 — Phosphoglucomutase 3
PGM3 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PGM3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Goblet cells | ERAD ER Homeostasis Protein processing & ER | ARF4, ATP2A2, C1orf122, DNAJB9, HERPUD1, JTB, LARP1B, SELENOK +1 more | View in SCUBA |
About the gene
| Synonyms | AGM1, DKFZP434B187, PAGM |
|---|---|
| Chromosome | 6: 83147324-83193936 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins |
| Molecular function | Isomerase |
| Biological process | Carbohydrate metabolism |
Function
Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O- glycosylation.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.