PLAGL1 — PLAG1 like zinc finger 1
PLAGL1 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PLAGL1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Immune Regulation Immune regulation | ADAT2, AFTPH, C2CD4B, CDKL2, CPEB4, DDHD1, FAM53B, FAS +10 more | View in SCUBA |
| Gamma-delta T cells | NK Receptor Expression cytotoxicity | CRACR2B, GFOD1, GPR171, GPR55, GSTM4, KIR2DL4, KLRC2, KLRC3 +4 more |
About the gene
| Synonyms | LOT1, ZAC |
|---|---|
| Chromosome | 6: 143940300-144064599 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors |
| Molecular function | Activator, DNA-binding |
| Biological process | Transcription, Transcription regulation |
Function
Acts as a transcriptional activator. Involved in the transcriptional regulation of type 1 receptor for pituitary adenylate cyclase-activating polypeptide
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.