BDP1 — B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
BDP1 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
BDP1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Transcription/RNA processing RNA processing | ANKRD17, CCDC97, CDK13, CHIC2, CLK4, CNOT6L, CRNKL1, ELF1 +29 more | View in SCUBA |
| Gamma-delta T cells | Chromatin Epigenetic Regulation DNA/chromatin regulation | ACIN1, ASH1L, BLTP1, CLTC, EPS15, EXOC2, FAM120B, GATAD2B +24 more | |
| Innate lymphoid cells | Splicing & Transcription RNA processing & translation | ACTR2, CDC5L, CYLD, DHX36, FXR1, GPATCH2, MTPN, PHF20L1 +12 more | View in SCUBA |
| Macrophages | RNA Processing Housekeeping Housekeeping | BAZ1A, CCAR1, CCDC88A, CLIP1, CUL5, DHX36, DNM1L, EP400 +32 more | View in SCUBA |
| Mucosal-associated invariant T cell | STAT3 Cytokine Signaling Inflammation | AKAP13, AKIRIN2, AKNA, ARGLU1, GOLGB1, H1-2, LCP1, PPP4R3B +4 more |
About the gene
| Synonyms | HSA238520, KIAA1241, KIAA1689, TAF3B1, TFC5, TFIIIB150, TFIIIB90, TFNR |
|---|---|
| Chromosome | 5: 71455651-71567820 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins |
| Molecular function | Activator |
| Biological process | Transcription, Transcription regulation |
Function
General activator of RNA polymerase III transcription. Requires for transcription from all three types of polymerase III promoters. Requires for transcription of genes with internal promoter elements and with promoter elements upstream of the initiation site
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.