POR — Cytochrome p450 oxidoreductase
POR belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
POR's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | Lipid-Sensing Transcriptional Lipid metabolism | ANKLE2, BAIAP2, C19orf25, C1orf52, COX19, CWC25, DEDD2, DNTTIP2 +29 more | View in SCUBA |
| Smooth muscle cells | Redox-Metabolic Housekeeping Housekeeping | COMT, DAD1, GSTO1, NDUFB5, PREPL, PSMA5, SEC61B | View in SCUBA |
About the gene
| Synonyms | CYPOR, FLJ26468 |
|---|---|
| Chromosome | 7: 75899200-75986855 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins |
| Molecular function | Oxidoreductase |
Function
This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.