SCUBA

NDUFB5 — NADH:ubiquinone oxidoreductase subunit B5

NDUFB5 belongs to a gene co-expression module in 8 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

NDUFB5's module in each cell type

Cell typeModuleShares the module with
CD19⁺ B cellsActin Cytoskeleton
Cytoskeletal
COTL1, GNAI2, HIGD2A, MOB1A, MPG, MYL12A, MYL12B, PRR13 +8 moreView in SCUBA
CD4⁺ T cellsOxidative Phosphorylation
Mitochondrial & OxPhos
ANP32B, ATP5MC2, C19orf53, COX7C, EIF3H, EIF3M, EMC7, GPX4 +10 moreView in SCUBA
Gamma-delta T cellsMitoribosome Small Subunit
Mitochondrial & OxPhos
ACADM, C14orf119, CHCHD1, COA3, COA4, COMMD8, GALK1, GEMIN6 +24 more
Glial cellsER-Mitochondria Housekeeping
Mitochondrial & OxPhos
CNN3, COX6C, HMGN3, LDHB, NDUFS8, PDIA3, TMBIM4, TMBIM6 +2 moreView in SCUBA
Goblet cellsOxidative Phosphorylation
Mitochondrial & OxPhos
ATP5MG, ATP5PO, COX4I1, COX6A1, COX6C, COX7C, ECH1, UQCRB +1 moreView in SCUBA
Lymphatic endothelialMitochondrial OxPhos Complex
Mitochondrial & OxPhos
COX6A1, COX6B1, COX6C, COX7A2, COX8A, DAD1, NDUFA1, NDUFB4 +6 moreView in SCUBA
MacrophagesComplex I / NADH Dehydrogenase
Mitochondrial & OxPhos
AHCY, ANP32A, ANTKMT, APEX1, ARL2, ATIC, ATP5F1A, ATP5ME +31 moreView in SCUBA
Smooth muscle cellsRedox-Metabolic Housekeeping
Housekeeping
COMT, DAD1, GSTO1, POR, PREPL, PSMA5, SEC61BView in SCUBA

About the gene

SynonymsCI-SGDH, MGC12314, SGDH
Chromosome3: 179604690-179627647
Predicted locationIntracellular, Membrane
Essential geneNo
Protein classMetabolic proteins, Predicted intracellular proteins, Predicted membrane proteins
Biological processElectron transport, Respiratory chain, Transport

Function

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.