CWC25 — CWC25 spliceosome associated protein homolog
CWC25 belongs to a gene co-expression module in 6 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CWC25's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Transcriptional regulation DNA/chromatin regulation | CCNH, DYNLL2, EIF2A, GOLGB1, IVNS1ABP, JMJD1C, KRR1, LPIN2 +8 more | View in SCUBA |
| Gamma-delta T cells | DNA Damage Ubiquitin DNA/chromatin regulation | ACBD3, CDADC1, CTPS1, FNIP1, ING3, KLHL18, RALGAPA1, RCOR1 +7 more | |
| Innate lymphoid cells | RNA Chromatin Regulation RNA processing & translation | BTBD7, CCDC59, DDX3Y, DNTTIP2, HNRNPU, KRR1, MRFAP1, PNRC2 +5 more | View in SCUBA |
| Macrophages | Lipid-Sensing Transcriptional Lipid metabolism | ANKLE2, BAIAP2, C19orf25, C1orf52, COX19, DEDD2, DNTTIP2, FBRS +29 more | View in SCUBA |
| Mucosal-associated invariant T cell | NF-κB Survival Signaling Immune regulation | BIRC2, GATA3, IL4I1, KPNA2, OAT, OTULIN, PIM2, RAB21 +4 more | |
| Natural Killer cells | NRF2 Stress Response Stress | C1orf56, CNOT6L, DDX18, FAM133B, JOSD1, KMT2E, NFE2L2, PRMT9 +2 more | View in SCUBA |
About the gene
| Synonyms | CCDC49, FLJ20291 |
|---|---|
| Chromosome | 17: 38800441-38825355 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Predicted intracellular proteins |
| Biological process | mRNA processing, mRNA splicing |
Function
Involved in pre-mRNA splicing as component of the spliceosome
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.