SCUBA

GSTO1 — Glutathione S-transferase omega 1

GSTO1 belongs to a gene co-expression module in 11 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

GSTO1's module in each cell type

Cell typeModuleShares the module with
CD4⁺ T cellsInterferon-stimulated genes
Anti-viral
APOBEC3G, ARPC4, ARPC5L, BAK1, BST2, DCTN3, ECH1, ETFB +14 moreView in SCUBA
CD8⁺ T cellsComplex I / OXPHOS
Mitochondrial & OxPhos
DAD1, GTF3C6, MANF, NDUFA12, NDUFA4, NDUFAB1, NDUFB3, NDUFS6 +1 moreView in SCUBA
EndothelialHousekeeping Metabolic
Housekeeping
ANXA5, ATP5MC3, CCT5, COX6B1, CTSL, DCTPP1, ERH, NDUFB7 +8 moreView in SCUBA
FibroblastsLysosomal Stress Response
Stress
ARPC1B, ATP6V0B, CTSB, FAM20C, IKBIP, MIF, PDLIM4, PKM +3 moreView in SCUBA
Gamma-delta T cellsCellular Homeostasis
Housekeeping
ANAPC11, BANF1, CALM3, CBX3, CBX5, COMMD4, DPM2, DUT +21 more
Innate lymphoid cellsmTOR Metabolic Stress
Stress
ADPGK, AKR1A1, ATP5IF1, BAX, CPNE1, GLO1, HNRNPR, JAGN1 +9 moreView in SCUBA
Lymphatic endothelialProteasome Assembly
Protein processing & ER
ARPC2, CSTB, DEGS1, MRPL14, PDCD5, POMP, PRELID1, PSMD7 +5 moreView in SCUBA
MacrophagesGlycolytic Redox Metabolism
Lipid metabolism
AGPAT2, ANXA5, ATP6V1F, BCKDK, BRI3, C1orf122, CLIC1, ELOC +18 moreView in SCUBA
Mucosal-associated invariant T cellCellular Housekeeping
Housekeeping
AKR7A2, ANP32A, ANXA5, AP1M1, APEX1, APOBEC3C, CDC26, DBNL +17 more
NeutrophilsGlycolytic Metabolism
Housekeeping
CSTB, CTSD, ENO1, FAM210A, GAPDH, GRN, LDHA, LGALS3 +4 more
Smooth muscle cellsRedox-Metabolic Housekeeping
Housekeeping
COMT, DAD1, NDUFB5, POR, PREPL, PSMA5, SEC61BView in SCUBA

About the gene

SynonymsGSTTLp28, P28
Chromosome10: 104235356-104267459
Predicted locationIntracellular
Essential geneNo
Protein classEnzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins
Molecular functionOxidoreductase, Transferase

Function

Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Also has glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid.

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.