PPFIA1 — PTPRF interacting protein alpha 1
PPFIA1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PPFIA1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | Microtubule Organization Cytoskeletal | CAMSAP2, DESI2, FAF2, HERPUD2, KCMF1, LSM14A, MAPK6, NRDC +14 more | View in SCUBA |
About the gene
| Synonyms | LIP.1, LIPRIN |
|---|---|
| Chromosome | 11: 70270690-70385312 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins |
Function
May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.