PRXL2C — Peroxiredoxin like 2C
PRXL2C belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PRXL2C's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | Autophagy Lysosomal Regulation Lysosomal & pahgocytosis | ADIPOR1, ARL8A, ATOSB, BCL10, BROX, CCR1, CEBPB, CHMP2B +22 more | View in SCUBA |
| Natural Killer cells | Housekeeping Mixed DNA regulation & transcription | ATP6V0C, ENSG00000285976, H2AJ, H3-3B, MARCHF3, NCBP2AS2, PNPLA2, TARS3 +1 more | View in SCUBA |
About the gene
| Synonyms | AAED1, C9orf21 |
|---|---|
| Chromosome | 9: 96639577-96655317 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
May positively regulate ERK1/2 signaling and AKT1 activation leading to HIF1A up-regulation with an increased expression of glycolysis genes and enhanced glycolysis
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.