RCAN2 — Regulator of calcineurin 2
RCAN2 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
RCAN2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | p53 DNA-damage response Stress | AEN, APOBEC3H, BBC3, DDB2, FDXR, GZMH, PHLDA3, PKIG | View in SCUBA |
| Endothelial | Capillary Endothelial Identity Endothelial cell development | ATOH8, AVPR2, BTNL9, C1QTNF9, CD300LG, CD34, CNFN, FAM13C +10 more | View in SCUBA |
| Fibroblasts | Quiescent Anti-inflammatory Fibroblast Developmental | ADIRF, CHCHD10, DACH1, FXYD6, IGFBP3, KHDRBS3, LSP1, NDRG2 +3 more | View in SCUBA |
About the gene
| Synonyms | DSCR1L1, ZAKI-4 |
|---|---|
| Chromosome | 6: 46220736-46491972 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.