SCUBA

RHPN2 — Rhophilin Rho GTPase binding protein 2

RHPN2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

RHPN2's module in each cell type

Cell typeModuleShares the module with
Goblet cellsEGF-Driven Wound Repair
Epithelial development
AREG, ARL14, C3orf52, CXCL8, F11R, HBEGF, NCOA7, RAP2B +1 moreView in SCUBA

About the gene

Chromosome19: 32978592-33064888
Predicted locationIntracellular
Essential geneNo
Protein classPredicted intracellular proteins

Function

Binds specifically to GTP-Rho. May function in a Rho pathway to limit stress fiber formation and/or increase the turnover of F-actin structures in the absence of high levels of RhoA activity

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.