CSRNP1 — Cysteine and serine rich nuclear protein 1

CSRNP1 belongs to a gene co-expression module in 13 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

CSRNP1's module in each cell type

Cell type	Module	Shares the module with
CD19⁺ B cells	Immediate Early NFkB BCR/AP1/NFKb pathway	ARL5B, CDKN1A, DUSP2, EGR1, EGR3, IER2, NFKBIA, PPP1R15B +3 more	View in SCUBA
CD4⁺ T cells	NF-kB Feedback Response TCR/AP1/NFKb pathway	ADGRE5, ARL5B, ATF3, NFKBIZ, PPP1R15B, RASGEF1B, TIPARP, TNFAIP3 +2 more	View in SCUBA
Fibroblasts	NF-κB Epigenetic Reprogramming Inflammatory	BCL3, BTG2, CDKN1A, DUSP5, EGR2, KDM6B, KLF10, LDLR +3 more	View in SCUBA
Gamma-delta T cells	ER Proteotoxic Stress Stress	ARL4A, BCAS2, CCDC59, CYCS, EIF5, EXOSC6, FOSB, HSPA5 +13 more
Glial cells	Integrated Stress Response Stress	ANKRD37, BAG3, CDKN1A, DDIT3, EGR2, EGR3, MCL1, MIDN +3 more	View in SCUBA
Innate lymphoid cells	NF-κB Inflammatory Activation Inflammation	CDKN1A, DUSP1, DUSP2, DUSP6, ELL2, EZR, FOS, ICAM1 +26 more	View in SCUBA
Lymphatic endothelial	Integrated Stress Response Stress	ATF3, DDIT3, DNAJA1, EIF4A2, HSP90AB1, PPP1R15A, RSRC2, SERTAD1 +2 more	View in SCUBA
Macrophages	NF-κB Activation Inflammatory	BCL3, BLOC1S6, CD83, CFLAR, CHMP1B, CNOT2, CYLD, DNAJB6 +33 more	View in SCUBA
Monocytes	Integrated Stress Response Stress	CDKN1A, EIF2AK3, HBEGF, KLF10, MAFF, PIM3, TIPARP	View in SCUBA
Mucosal-associated invariant T cell	NF-κB Negative Feedback Immune regulation	ARL4A, BCAS2, CXCR4, ENSG00000285976, IDS, ITPRIP, NFKBIA, NFKBIB +7 more
Natural Killer cells	NF-κB Activation Inflammation	ADGRE5, BCL3, BHLHE40, DUSP10, NFKB1, NFKB2, NINJ1, OTULIN +3 more	View in SCUBA
Neutrophils	Inflammasome IL-1 Response Cytokine & chemokine secretion	EGR3, G0S2, IER3, IFRD1, IL1B, IL1RN, IVNS1ABP, LPCAT1 +5 more
Smooth muscle cells	Secondary Response Genes Stress	ABHD2, BCL6, ECM2, GADD45A, HRH2, LITAF, MAT2A, MCL1 +3 more	View in SCUBA

About the gene

Synonyms	AXUD1, DKFZp566F164, FAM130B, TAIP-3, URAX1
Chromosome	3: 39141855-39154562
Predicted location	Intracellular
Essential gene	No
Protein class	Predicted intracellular proteins, Transcription factors
Molecular function	Activator, DNA-binding
Biological process	Apoptosis, Transcription, Transcription regulation

Function

Binds to the consensus sequence 5'-AGAGTG-3' and has transcriptional activator activity (By similarity). May have a tumor- suppressor function. May play a role in apoptosis.

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.