ARL14 — ADP ribosylation factor like GTPase 14
ARL14 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ARL14's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Brush border lipid handling Absorption | ABCG1, ABHD12, CDHR2, ENTPD8, IDS, PNPLA2, RAI14, SEMA3G +2 more | View in SCUBA |
| Goblet cells | EGF-Driven Wound Repair Epithelial development | AREG, C3orf52, CXCL8, F11R, HBEGF, NCOA7, RAP2B, RHPN2 +1 more | View in SCUBA |
About the gene
| Synonyms | ARF7, FLJ22595 |
|---|---|
| Chromosome | 3: 160677160-160678448 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
GTPase that recruits MYO1E to MHC class II-containing vesicles via the effector protein ARL14EP and hence controls the movement of these vesicles along the actin cytoskeleton in dendritic cells
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.