SAPCD2 — Suppressor APC domain containing 2
SAPCD2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SAPCD2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Goblet cells | G2/M Cyclin Program Cell cycle | ARL6IP1, CCNB1, CCNB2, CDC20, CENPE, CENPF, CEP55, DLGAP5 +5 more | View in SCUBA |
About the gene
| Synonyms | C9orf140, p42.3 |
|---|---|
| Chromosome | 9: 137062127-137070557 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Biological process | Cell cycle, Cell division, Mitosis |
Function
Plays a role in planar mitotic spindle orientation in retinal progenitor cells (RPCs) and promotes the production of symmetric terminal divisions (By similarity). Negatively regulates the mitotic apical cortex localization of GPSM2. Involved also in positive regulation of cell proliferation and tumor cell growth.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.