CEP55 — Centrosomal protein 55
CEP55 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CEP55's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | Cell Cycle Proliferation Cell cycle | ALYREF, ANP32E, BCL2L12, BIRC5, BUB3, CENPW, CKS1B, DTYMK +4 more | View in SCUBA |
| CD8⁺ T cells | Mitosis & Cytokinesis Cell cycle | CDCA2, CKAP2L, NUSAP1, RACGAP1, SGO1, TACC3, TOP2A | View in SCUBA |
| Goblet cells | G2/M Cyclin Program Cell cycle | ARL6IP1, CCNB1, CCNB2, CDC20, CENPE, CENPF, DLGAP5, HMMR +5 more | View in SCUBA |
| Hematopoietic progenitor cells | Mitotic Spindle Cell cycle | BIRC5, CCNB2, CDC20, CDKN3, DLGAP5, HMMR, MKI67, TPX2 +1 more | |
| Macrophages | Mitotic Spindle Cell cycle | ANLN, ASPM, AURKA, BIRC5, CCNA2, CCNB1, CCNB2, CDK1 +14 more | View in SCUBA |
About the gene
| Synonyms | C10orf3, CT111, FLJ10540 |
|---|---|
| Chromosome | 10: 93496612-93529092 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins |
| Molecular function | Developmental protein |
| Biological process | Cell cycle, Cell division, Mitosis |
Function
Plays a role in mitotic exit and cytokinesis. Recruits PDCD6IP and TSG101 to midbody during cytokinesis. Required for successful completion of cytokinesis. Not required for microtubule nucleation. Plays a role in the development of the brain and kidney.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.