CKAP2 — Cytoskeleton associated protein 2
CKAP2 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CKAP2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | DNA repair/replication DNA/chromatin regulation | ACAP2, BROX, CCDC88C, EPM2AIP1, FOXO3, HAUS3, HELB, KMT2C +4 more | View in SCUBA |
| CD8⁺ T cells | S-phase Chromatin Replication Cell cycle | ANP32E, BRCA2, HDGF, HP1BP3, LBR, MIS18BP1, NSD2, NUCKS1 +4 more | View in SCUBA |
| Endothelial | Mitotic Spindle Cell cycle | ASPM, CCNB1, CDK1, CENPE, CENPF, KIF20B, KNSTRN, LMNB1 +14 more | View in SCUBA |
| Smooth muscle cells | Anaphase Cytokinesis Cell cycle | ANLN, CCNB2, CDC20, CENPF, DEPDC1, PRC1, PTTG1 | View in SCUBA |
About the gene
| Synonyms | FLJ10749, LB1, se20-10, TMAP |
|---|---|
| Chromosome | 13: 52455429-52476628 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Biological process | Apoptosis, Cell cycle |
Function
Possesses microtubule stabilizing properties. Involved in regulating aneuploidy, cell cycling, and cell death in a p53/TP53- dependent manner (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.