DLGAP5 — DLG associated protein 5
DLGAP5 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
DLGAP5's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | G2/M Mitosis Cell cycle | AURKA, BUB1, CCDC34, CCNB1, CCNB2, CDC20, CDKN3, CENPA +7 more | View in SCUBA |
| CD8⁺ T cells | Mitotic Spindle Cell cycle | ASPM, BUB1, CENPA, CENPE, CENPF, GTSE1, HMMR, KIF14 +6 more | View in SCUBA |
| Goblet cells | G2/M Cyclin Program Cell cycle | ARL6IP1, CCNB1, CCNB2, CDC20, CENPE, CENPF, CEP55, HMMR +5 more | View in SCUBA |
| Hematopoietic progenitor cells | Mitotic Spindle Cell cycle | BIRC5, CCNB2, CDC20, CDKN3, CEP55, HMMR, MKI67, TPX2 +1 more |
About the gene
| Synonyms | DLG1, DLG7, HURP, KIAA0008 |
|---|---|
| Chromosome | 14: 55148112-55191608 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins |
| Biological process | Cell cycle |
Function
Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.