CCNB1 — Cyclin B1
CCNB1 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CCNB1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | G2/M Mitosis Cell cycle | AURKA, BUB1, CCDC34, CCNB2, CDC20, CDKN3, CENPA, DLGAP5 +7 more | View in SCUBA |
| CD8⁺ T cells | Mitotic Kinase Cascade Cell cycle | AURKA, CCNB2, CDC20, CDC25B, DEPDC1, FAM72C, FAM72D, KIF20A +6 more | View in SCUBA |
| Endothelial | Mitotic Spindle Cell cycle | ASPM, CDK1, CENPE, CENPF, CKAP2, KIF20B, KNSTRN, LMNB1 +14 more | View in SCUBA |
| Goblet cells | G2/M Cyclin Program Cell cycle | ARL6IP1, CCNB2, CDC20, CENPE, CENPF, CEP55, DLGAP5, HMMR +5 more | View in SCUBA |
| Macrophages | Mitotic Spindle Cell cycle | ANLN, ASPM, AURKA, BIRC5, CCNA2, CCNB2, CDK1, CDKN2C +14 more | View in SCUBA |
About the gene
| Synonyms | CCNB |
|---|---|
| Chromosome | 5: 69167135-69178245 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins, Transporters |
| Molecular function | Cyclin |
| Biological process | Cell cycle, Cell division, Mitosis |
Function
Essential for the control of the cell cycle at the G2/M (mitosis) transition.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.