Oxidative Phosphorylation
Gene co-expression module in CD19⁺ B cells
| Category | Mitochondrial & OxPhos |
|---|---|
| Genes | 9 |
| Annotation certainty | 4 of 5 |
| Annotation consistency | 4 of 9 genes have a known function matching the annotation |
Why this annotation
Top genes include ATP5F1E, ATP5MC2 (ATP synthase), UQCR11 (Complex III), COX7A2 (Complex IV) — mitochondrial OxPhos. Also several housekeeping/translation-associated small genes (SRP14, TMA7, C19orf53, EDF1, OST4). Core coherence, uniform expression. This is a mixed OxPhos/housekeeping module but OxPhos dominates the hubs alongside M19 neighbor context.
Genes
ATP5F1E, ATP5MC2, C19orf53, COX7A2, EDF1, OST4, SRP14, TMA7, UQCR11
Most correlated modules
- Oxidative Phosphorylation · correlation 0.95
- Oxidative Phosphorylation · correlation 0.93
- Glycolysis OxPhos · correlation 0.91
- Actin Cytoskeleton · correlation 0.91
- Oxidative Phosphorylation · correlation 0.90
- Spliceosome snRNP · correlation 0.88
- Actin Cytoskeleton · correlation 0.86
- Actin Cytoskeleton · correlation 0.86
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.