Amino acid absorption
Gene co-expression module in Enterocytes
| Category | Absorption |
|---|---|
| Genes | 11 |
| Annotation certainty | 4 of 5 |
| Annotation consistency | 8 of 11 genes have a known function matching the annotation |
Why this annotation
Cationic/neutral amino acid transporters (SLC7A7, SLC7A9, SLC3A1) form the brush-border b0,+ system. Additional absorptive genes include vitamin B12 transport (TCN2), trehalase (TREH), aminoacylase (ACY3), PRAP1 and LEAP2. Together these mark proximal-type absorptive enterocytes for nutrient uptake.
Genes
ACY3, DHRS7, ERICH4, LEAP2, PRAP1, SLC3A1, SLC7A7, SLC7A9, TCN2, TMEM220, TREH
Most correlated modules
- Villus-tip enterocyte transport · correlation 0.95
- Enterocyte lipid metabolism · correlation 0.93
- Amino acid absorption · correlation 0.93
- Chylomicron lipid absorption · correlation 0.92
- Brush-border nutrient uptake · correlation 0.90
- Brush-border Nutrient Uptake · correlation 0.89
- Enterocyte lipid trafficking · correlation 0.86
- Mature enterocyte differentiation · correlation 0.85
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.