TCN2 — Transcobalamin 2
TCN2 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TCN2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | IL-13/STAT6 Signaling Inflammation | ABLIM1, ARL2BP, ASRGL1, ATP8B1, BMP1, BMPR2, CLIP1, CMIP +18 more | View in SCUBA |
| Enterocytes | Amino acid absorption Absorption | ACY3, DHRS7, ERICH4, LEAP2, PRAP1, SLC3A1, SLC7A7, SLC7A9 +2 more | View in SCUBA |
| Monocytes | Stress-Adapted Macrophage Stress | DDIT4, KAT2A, MS4A4E, NOTCH2NLA, SESN1, SIAH2, SIGLEC11 | View in SCUBA |
About the gene
| Synonyms | D22S676, D22S750, TC2 |
|---|---|
| Chromosome | 22: 30607003-30627271 |
| Predicted location | Intracellular, Secreted |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins |
| Biological process | Cobalt transport, Ion transport, Transport |
Function
Primary vitamin B12-binding and transport protein. Delivers cobalamin to cells
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.