ACTG2 — Actin gamma 2, smooth muscle
ACTG2 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ACTG2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Smooth Muscle Identity Cytoskeletal | ALDH1B1, C3orf70, CNN1, FBXL22, HSD17B6, JPH2, KCNH2, KCNMB1 +12 more | View in SCUBA |
| Smooth muscle cells | SMC Contractile Apparatus Contractility | CFL2, CKB, CSRP1, FLNA, ILK, LMOD1, MYH11, PPP1R12B +3 more | View in SCUBA |
About the gene
| Synonyms | ACTA3, ACTL3, ACTSG |
|---|---|
| Chromosome | 2: 73892314-73919865 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins |
| Molecular function | Hydrolase, Muscle protein |
Function
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.