ALDH1B1 — Aldehyde dehydrogenase 1 family member B1
ALDH1B1 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ALDH1B1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Smooth Muscle Identity Cytoskeletal | ACTG2, C3orf70, CNN1, FBXL22, HSD17B6, JPH2, KCNH2, KCNMB1 +12 more | View in SCUBA |
| Smooth muscle cells | Integrin adhesion complex Migration & adhesion | ALDH2, DST, FERMT2, ITGA5, KLHL42, METTL7A, NFIX, NPTN +3 more | View in SCUBA |
About the gene
| Synonyms | ALDH5, ALDHX |
|---|---|
| Chromosome | 9: 38392702-38398661 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Predicted intracellular proteins |
| Molecular function | Oxidoreductase |
Function
ALDHs play a major role in the detoxification of alcohol- derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.