LMOD1 — Leiomodin 1
LMOD1 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
LMOD1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Smooth Muscle Identity Cytoskeletal | ACTG2, ALDH1B1, C3orf70, CNN1, FBXL22, HSD17B6, JPH2, KCNH2 +12 more | View in SCUBA |
| Pericytes | Pericyte Identity Differentiation Developmental | ADAMTS5, ARHGAP15, EPB41L2, GUCY1A1, INPP4B, LGI4, MAP1LC3A, NFASC +11 more | View in SCUBA |
| Smooth muscle cells | SMC Contractile Apparatus Contractility | ACTG2, CFL2, CKB, CSRP1, FLNA, ILK, MYH11, PPP1R12B +3 more | View in SCUBA |
About the gene
| Synonyms | 1D, 64kD, D1, SM-LMOD, SMLMOD |
|---|---|
| Chromosome | 1: 201896456-201946588 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Actin-binding |
Function
Required for proper contractility of visceral smooth muscle cells. Mediates nucleation of actin filaments
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.