ATP11B — ATPase phospholipid transporting 11B (putative)
ATP11B belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ATP11B's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Integrin adhesion migration & adhesion | CD84, CEP85L, CYTH1, HTRA1, ITGAL, MYO7A, PCNX2, PDE4DIP +4 more | View in SCUBA |
| Gamma-delta T cells | RNA Binding/Splicing RNA processing & translation | AIMP1, C1orf43, CCT2, DEDD2, DGKD, ENSA, ENY2, FBXL14 +18 more |
About the gene
| Synonyms | ATPIF, ATPIR, KIAA0956 |
|---|---|
| Chromosome | 3: 182793503-182921629 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Enzymes, Predicted membrane proteins, Transporters |
| Molecular function | Translocase |
| Biological process | Lipid transport, Transport |
Function
Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids, phosphatidylserines (PS) and phosphatidylethanolamines (PE), from the outer to the inner leaflet of intracellular membranes. May contribute to the maintenance of membrane lipid asymmetry in endosome compartment
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.