SLC44A4 — Solute carrier family 44 member 4
SLC44A4 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SLC44A4's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Colonocyte terminal differentiation Epithelial development | CCDC186, CEACAM1, CMPK1, FHL2, GCNT3, HKDC1, IFNGR1, LRRFIP1 +2 more | View in SCUBA |
About the gene
| Synonyms | C6orf29, CTL4, DFNA72, FLJ14491, NG22, TPPT |
|---|---|
| Chromosome | 6: 31863192-31879046 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters |
| Biological process | Antiport, Transport |
Function
Choline transporter that plays a role in the choline- acetylcholine system and is required to the efferent innervation of hair cells in the olivocochlear bundle for the maintenance of physiological function of outer hair cells and the protection of hair cells from acoustic injury (By similarity). Also described as a thiamine pyrophosphate transporter in colon, may mediate the absorption of microbiota- generated thiamine pyrophosphate and contribute to host thiamine (vitamin B1) homeostasis. Also has thiamine pyrophosphate transporter activity
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.