VCAN — Versican
VCAN belongs to a gene co-expression module in 6 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
VCAN's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | BMP-ECM Fibroblast ECM remodeling | ACVRL1, CLEC11A, GNG11, ITGB5, LAMA2, MRC2, TFPI | View in SCUBA |
| Glial cells | Enteric Glial Homeostasis Housekeeping | APOE, BCHE, CCND3, COL12A1, ENTPD2, FXYD6, NPDC1, PAQR6 +5 more | View in SCUBA |
| Macrophages | Inflammatory Monocyte Activation Inflammatory | ANPEP, AQP9, CD300E, CD82, CLEC5A, CXXC5, DDX60L, DHRS9 +25 more | View in SCUBA |
| Monocytes | Classical Monocyte Activation Inflammatory | CAPG, LGALS1, LYZ, MCEMP1, PDLIM7, S100A8, S100A9, SERPINB1 +1 more | View in SCUBA |
| Pericytes | Stromal ECM Production ECM production | ABCA8, CCL11, CFD, CTSK, DCN, FBLN1, LUM, MFAP4 | View in SCUBA |
| Smooth muscle cells | Matrix Crosslinking Activation ECM remodeling | ADAM19, COL23A1, FOXF1, LOXL2, NKX2-3, PLPP1, RCN1 | View in SCUBA |
About the gene
| Synonyms | CSPG2, PG-M |
|---|---|
| Chromosome | 5: 83471618-83582303 |
| Predicted location | Intracellular, Secreted |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins |
Function
May play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation. Binds hyaluronic acid
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.