DDX3Y — DEAD-box helicase 3 Y-linked
DDX3Y belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
DDX3Y's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Innate lymphoid cells | RNA Chromatin Regulation RNA processing & translation | BTBD7, CCDC59, CWC25, DNTTIP2, HNRNPU, KRR1, MRFAP1, PNRC2 +5 more | View in SCUBA |
| Mucosal-associated invariant T cell | MAIT Cell Identity T cell maturation | AFF3, DKK3, DSE, EPAS1, FKBP5, FYN, GLIPR1, H1-10 +16 more |
About the gene
| Synonyms | DBY |
|---|---|
| Chromosome | Y: 12904108-12920478 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins |
| Molecular function | DNA-binding, Helicase, Hydrolase, RNA-binding |
Function
Probable ATP-dependent RNA helicase. During immune response, may enhance IFNB1 expression via IRF3/IRF7 pathway (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.